منابع مشابه
Optimizing antibiotic therapy in the intensive care unit setting
Antibiotics are one of the most common therapies administered in the intensive care unit setting. In addition to treating infections, antibiotic use contributes to the emergence of resistance among pathogenic microorganisms. Therefore, avoiding unnecessary antibiotic use and optimizing the administration of antimicrobial agents will help to improve patient outcomes while minimizing further pres...
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There has been little improvement in septic shock mortality in the past 70 years, despite ever more broad-spectrum and potent antimicrobials. In the past, resuscitative elements have been the primary area of clinical septic shock management and research. The question of the optimal use of antimicrobial therapy was relatively ignored in recent decades. This review explores the pathophysiology of...
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Our understanding of the etiology, pathogenesis and consequences of acute exacerbations of chronic obstructive pulmonary disease (COPD) has increased substantially in the last decade. Several new lines of evidence demonstrate that bacterial isolation from sputum during acute exacerbation in many instances reflects a cause-effect relationship. Placebo-controlled antibiotic trials in exacerbation...
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The advent of each new antibiotic is not an unmixed blessing. The advantage of acquiring another agent whose range of antibacterial activity parallels that of already existing antibiotics is somewhat offset by the necessity of re-evaluating the known in the light of the new unknown. And involved is not just the effectiveness of one agent versus another, but the relative cost, potential toxicity...
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ژورنال
عنوان ژورنال: Microbe Magazine
سال: 2006
ISSN: 1558-7452,1558-7460
DOI: 10.1128/microbe.1.304.2